Indalpine
This selective serotonin reuptake inhibitor (SSRI) was one of the earliest drugs in its class, developed in France to treat depression by increasing serotonin levels in the brain. It was withdrawn from clinical use due to rare but serious blood cell disorders.
Masse moléculaire
228,3300 g/mol
LogP
3,30
TPSA
27,80 Ų
Règle des 5 de Lipinski
Conforme
Mécanisme d'action
Selectively inhibits the serotonin reuptake transporter (SERT) at presynaptic neurons, increasing serotonin concentration in the synaptic cleft. This enhanced serotonergic neurotransmission is associated with antidepressant and anxiolytic effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively inhibits the serotonin reuptake transporter (SERT) at presynaptic neurons, increasing serotonin concentration in the synaptic cleft. This enhanced serotonergic neurotransmission is associated with antidepressant and anxiolytic effects.
Structure 2D
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SMILES
c1ccc2c(CCC3CCNCC3)c[nH]c2c1
InChI
InChI=1S/C15H20N2/c1-2-4-15-14(3-1)13(11-17-15)6-5-12-7-9-16-10-8-12/h1-4,11-12,16-17H,5-10H2
Molecular Formula
C15H20N2
HBD / HBA
2 / 1
Liaisons Rotatives
3
Atomes Lourds
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
This selective serotonin reuptake inhibitor (SSRI) was one of the earliest drugs in its class, developed in France to treat depression by increasing serotonin levels in the brain. It was withdrawn from clinical use due to rare but serious blood cell disorders.
Selectively inhibits the serotonin reuptake transporter (SERT) at presynaptic neurons, increasing serotonin concentration in the synaptic cleft. This enhanced serotonergic neurotransmission is associated with antidepressant and anxiolytic effects.
Yes, Indalpine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL276520. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 44668. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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