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Indalpine

CHEMBL276520 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
228.3 g/mol
LogP
3.3
Phase
4

This selective serotonin reuptake inhibitor (SSRI) was one of the earliest drugs in its class, developed in France to treat depression by increasing serotonin levels in the brain. It was withdrawn from clinical use due to rare but serious blood cell disorders.

Khối lượng phân tử

228,3300 g/mol

LogP

3,30

TPSA

27,80 Ų

Lipinski RO5

Đạt

Cơ chế tác dụng

Selectively inhibits the serotonin reuptake transporter (SERT) at presynaptic neurons, increasing serotonin concentration in the synaptic cleft. This enhanced serotonergic neurotransmission is associated with antidepressant and anxiolytic effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Selectively inhibits the serotonin reuptake transporter (SERT) at presynaptic neurons, increasing serotonin concentration in the synaptic cleft. This enhanced serotonergic neurotransmission is associated with antidepressant and anxiolytic effects.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
c1ccc2c(CCC3CCNCC3)c[nH]c2c1

                

                

                
                

                    
InChI

                    
InChI=1S/C15H20N2/c1-2-4-15-14(3-1)13(11-17-15)6-5-12-7-9-16-10-8-12/h1-4,11-12,16-17H,5-10H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H20N2

                    

                    
                    

                        
HBD / HBA

                        
2 / 1

                    

                    
                    

                        
Liên kết có thể quay

                        
3

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This selective serotonin reuptake inhibitor (SSRI) was one of the earliest drugs in its class, developed in France to treat depression by increasing serotonin levels in the brain. It was withdrawn from clinical use due to rare but serious blood cell disorders.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Selectively inhibits the serotonin reuptake transporter (SERT) at presynaptic neurons, increasing serotonin concentration in the synaptic cleft. This enhanced serotonergic neurotransmission is associated with antidepressant and anxiolytic effects.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Indalpine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL276520.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 44668.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.