Linezolid

CHEMBL126 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

337.4 g/mol

LogP

0.7

Phase

4

An oxazolidinone antibiotic used to treat serious gram-positive bacterial infections, including MRSA and vancomycin-resistant enterococci. It works by blocking the early stage of bacterial protein synthesis at the ribosomal level.

Masse moléculaire

337,3500 g/mol

LogP

0,70

TPSA

71,10 Å²

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Bladder Cancer Infectious Disease Chronic Kidney Disease Type 2 Diabetes Tuberculosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CC(=O)NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1

InChI

InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

Molecular Formula

C16H20FN3O4

HBD / HBA

1 / 6

Liaisons Rotatives

4

Atomes Lourds

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

An oxazolidinone antibiotic used to treat serious gram-positive bacterial infections, including MRSA and vancomycin-resistant enterococci. It works by blocking the early stage of bacterial protein synthesis at the ribosomal level.

Yes, Linezolid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL126. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 441401. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C16H20FN3O4
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.