Losartan Potassium

CHEMBL995 Phase 4 Approuvé Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
461.0 g/mol
LogP
Phase
4

The potassium salt form of losartan, the standard pharmaceutical preparation of this ARB antihypertensive drug. It is widely used for hypertension, heart failure, and kidney protection in diabetes.

Masse moléculaire

461,0000 g/mol

TPSA

77,70 Ų

Aires thérapeutiques

Mécanisme d'action

Angiotensin II receptor type 1 antagonist.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Angiotensin II receptor type 1 antagonist.

Structure 2D

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SMILES

CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[n-]2)cc1.[K+]

InChI

InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1

Molecular Formula

C22H22ClKN6O

HBD / HBA

1 / 6

Liaisons Rotatives

8

Atomes Lourds

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

The potassium salt form of losartan, the standard pharmaceutical preparation of this ARB antihypertensive drug. It is widely used for hypertension, heart failure, and kidney protection in diabetes.

Angiotensin II receptor type 1 antagonist.

Yes, Losartan Potassium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL995. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11751549. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.