Netupitant

CHEMBL206253 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

578.6 g/mol

LogP

6.8

Phase

4

This medication is used in combination with another drug to prevent nausea and vomiting caused by cancer chemotherapy. It works by blocking substance P receptors in the brain that trigger the vomiting reflex, and is taken as a single oral dose before chemotherapy.

Masse moléculaire

578,6000 g/mol

LogP

6,80

TPSA

39,70 Å²

Règle des 5 de Lipinski

Non conforme

Aires thérapeutiques

Oncology Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

Cc1ccccc1-c1cc(N2CCN(C)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1

InChI

InChI=1S/C30H32F6N4O/c1-19-8-6-7-9-23(19)24-17-26(40-12-10-38(4)11-13-40)37-18-25(24)39(5)27(41)28(2,3)20-14-21(29(31,32)33)16-22(15-20)30(34,35)36/h6-9,14-18H,10-13H2,1-5H3

Molecular Formula

C30H32F6N4O

HBD / HBA

- / 10

Liaisons Rotatives

5

Atomes Lourds

41

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This medication is used in combination with another drug to prevent nausea and vomiting caused by cancer chemotherapy. It works by blocking substance P receptors in the brain that trigger the vomiting reflex, and is taken as a single oral dose before chemotherapy.

Yes, Netupitant is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL206253. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6451149. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C30H32F6N4O
Synonymes: 1

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.