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Norfloxacin

CHEMBL9 Phase 4 Approuvé Small molecule
Half-Life
3-4 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
319.3 g/mol
LogP
-1.0
Phase
4

A fluoroquinolone antibiotic used to treat urinary tract infections by stopping bacterial DNA replication.

Masse moléculaire

319,3310 g/mol

LogP

-1,00

TPSA

72,90 Ų

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Hypertension

Classes de médicaments

J — J - Antiinfectives for Systemic Use

Mécanisme d'action

Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

Pharmacokinetics (PK)

Half-Life 3-4 hours

Pharmacodynamics (PD)

Mécanisme

Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21

                

                

                
                

                    
InChI

                    
InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H18FN3O3

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
Liaisons Rotatives

                        
3

                    

                    
                    
                    

                        
Atomes Lourds

                        
23

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
A fluoroquinolone antibiotic used to treat urinary tract infections by stopping bacterial DNA replication.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Norfloxacin: Half-life: 3-4 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Norfloxacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Amoxicillin
                            Small molecule
                        
                        
                        
                            Azithromycin
                            Small molecule
                        
                        
                        
                            Ciprofloxacin
                            Small molecule
                        
                        
                        
                            Doxycycline
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL9.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4539.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.