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Oseltamivir

CHEMBL1229 Phase 4 Approuvé Small molecule
Half-Life
6-10 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
312.4 g/mol
LogP
1.1
Phase
4

A neuraminidase inhibitor, oseltamivir treats and prevents influenza by blocking the enzyme that newly formed viral particles use to detach from infected cells, limiting the virus's spread through the respiratory tract. Marketed as Tamiflu, it has the formula C16H28N2O4 and is most effective when started within 48 hours of symptom onset.

An antiviral neuraminidase inhibitor for treating and preventing influenza, most effective within 48 hours.

Masse moléculaire

312,4050 g/mol

LogP

1,10

TPSA

90,70 Ų

Règle des 5 de Lipinski

Conforme

Aires thérapeutiques

Infectious Disease

Classes de médicaments

J — J - Antiinfectives for Systemic Use

Mécanisme d'action

Neuraminidase inhibitor preventing viral release from host cells.

Pharmacokinetics (PK)

Half-Life 6-10 hours

Pharmacodynamics (PD)

Mécanisme

Neuraminidase inhibitor preventing viral release from host cells.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H28N2O4

                    

                    
                    

                        
HBD / HBA

                        
2 / 5

                    

                    
                    

                        
Liaisons Rotatives

                        
8

                    

                    
                    
                    

                        
Atomes Lourds

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                

                    
                    
                        

                            

  
  Minor


                            
                                Oseltamivir + Warfarin
                            
                        

                        
                        
Oseltamivir does not appear to meaningfully alter warfarin pharmacokinetics; however, the febrile illness being treated may independently elevate INR, which can be mistakenly attributed to the antiviral.

                        
                    
                    
                    
                        

                            

  
  Minor


                            
                                Oseltamivir + Methotrexate
                            
                        

                        
                        
Both oseltamivir carboxylate and methotrexate rely on renal tubular secretion via OAT transporters; theoretically, competition could reduce elimination of either drug, though clinical evidence of a significant interaction is limited.

                        
                    
                    
                

                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
An antiviral neuraminidase inhibitor for treating and preventing influenza, most effective within 48 hours.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Neuraminidase inhibitor preventing viral release from host cells.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Oseltamivir: Half-life: 6-10 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Oseltamivir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            
            

                
                
                    ADME Journey →
                
                
                
            

            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Amoxicillin
                            Small molecule
                        
                        
                        
                            Azithromycin
                            Small molecule
                        
                        
                        
                            Ciprofloxacin
                            Small molecule
                        
                        
                        
                            Doxycycline
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1229.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 65028.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.