Oxyphenbutazone

CHEMBL3989676 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

324.4 g/mol

LogP

2.7

Phase

4

A nonsteroidal anti-inflammatory drug (NSAID) derived from phenylbutazone, used to treat pain and inflammation in conditions such as arthritis and gout. It has been largely withdrawn from many markets due to serious bone marrow toxicity.

Masse moléculaire

324,4000 g/mol

LogP

2,70

TPSA

60,90 Å²

Règle des 5 de Lipinski

Conforme

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCCCC1C(=O)N(c2ccccc2)N(c2ccc(O)cc2)C1=O.O

InChI

InChI=1S/C19H20N2O3.H2O/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-10-12-16(22)13-11-15;/h4-8,10-13,17,22H,2-3,9H2,1H3;1H2

Molecular Formula

C19H20N2O3

HBD / HBA

1 / 3

Liaisons Rotatives

5

Atomes Lourds

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

A nonsteroidal anti-inflammatory drug (NSAID) derived from phenylbutazone, used to treat pain and inflammation in conditions such as arthritis and gout. It has been largely withdrawn from many markets due to serious bone marrow toxicity.

Yes, Oxyphenbutazone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989676. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4641. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C19H20N2O3

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.