Relatlimab

CHEMBL3990044 Phase 4 Approuvé Antibody
Half-Life
Bioavailability
Protein Binding
Molecular Weight
g/mol
LogP
Phase
4

Relatlimab is a human monoclonal antibody that inhibits lymphocyte activation gene-3 (LAG-3), an immune checkpoint receptor expressed on exhausted T cells that suppresses antitumor immune responses when engaged by MHC class II ligands. In combination with nivolumab (anti-PD-1), relatlimab provides dual checkpoint blockade that synergistically restores T-cell function against tumors, with approval for unresectable or metastatic melanoma.

Aires thérapeutiques

Mécanisme d'action

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

Relatlimab is a human monoclonal antibody that inhibits lymphocyte activation gene-3 (LAG-3), an immune checkpoint receptor expressed on exhausted T cells that suppresses antitumor immune responses when engaged by MHC class II ligands. In combination with nivolumab (anti-PD-1), relatlimab provides dual checkpoint blockade that synergistically restores T-cell function against tumors, with approval for unresectable or metastatic melanoma.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Relatlimab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3990044. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.