Sinecatechins
Sinecatechins is a botanical drug consisting of a partially purified fraction of green tea (Camellia sinensis) catechins, including epigallocatechin gallate (EGCG) as the major component, approved for topical treatment of external anogenital warts caused by human papillomavirus (HPV). The catechins exert antiviral, immunomodulatory, antiproliferative, and antioxidant activities that collectively contribute to clearance of HPV-related warts. It is the first botanical prescription drug approved by the FDA.
Mécanisme d'action
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
Sinecatechins is a botanical drug consisting of a partially purified fraction of green tea (Camellia sinensis) catechins, including epigallocatechin gallate (EGCG) as the major component, approved for topical treatment of external anogenital warts caused by human papillomavirus (HPV). The catechins exert antiviral, immunomodulatory, antiproliferative, and antioxidant activities that collectively contribute to clearance of HPV-related warts. It is the first botanical prescription drug approved by the FDA.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Sinecatechins is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201723. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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