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Sinecatechins

CHEMBL1201723 Phase 4 Approved Unknown
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Sinecatechins is a botanical drug consisting of a partially purified fraction of green tea (Camellia sinensis) catechins, including epigallocatechin gallate (EGCG) as the major component, approved for topical treatment of external anogenital warts caused by human papillomavirus (HPV). The catechins exert antiviral, immunomodulatory, antiproliferative, and antioxidant activities that collectively contribute to clearance of HPV-related warts. It is the first botanical prescription drug approved by the FDA.

Mechanism of Action

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Sinecatechins is a botanical drug consisting of a partially purified fraction of green tea (Camellia sinensis) catechins, including epigallocatechin gallate (EGCG) as the major component, approved for topical treatment of external anogenital warts caused by human papillomavirus (HPV). The catechins exert antiviral, immunomodulatory, antiproliferative, and antioxidant activities that collectively contribute to clearance of HPV-related warts. It is the first botanical prescription drug approved by the FDA.

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Yes, Sinecatechins is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201723. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.