Sulbactam
A beta-lactamase inhibitor that protects penicillin-type antibiotics from being destroyed by bacterial enzymes, thereby restoring their effectiveness against resistant bacteria. It is used in combination with ampicillin to treat intra-abdominal infections, gynecological infections, and skin infections caused by resistant organisms.
Masse moléculaire
233,2400 g/mol
LogP
-1,00
TPSA
100,00 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
Embed this structure
SMILES
CC1(C)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O
InChI
InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1
Molecular Formula
C8H11NO5S
HBD / HBA
1 / 5
Liaisons Rotatives
1
Atomes Lourds
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
A beta-lactamase inhibitor that protects penicillin-type antibiotics from being destroyed by bacterial enzymes, thereby restoring their effectiveness against resistant bacteria. It is used in combination with ampicillin to treat intra-abdominal infections, gynecological infections, and skin infections caused by resistant organisms.
Yes, Sulbactam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL403. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 130313. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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