Sulfacytine

CHEMBL1201056 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

294.3 g/mol

LogP

0.1

Phase

4

Sulfacytine is a short-acting sulfonamide antibiotic used for the treatment of acute, uncomplicated urinary tract infections caused by susceptible bacteria. It inhibits bacterial dihydropteroate synthase, blocking folate synthesis and selectively killing bacteria that must synthesize their own folic acid. Its use has declined with the emergence of sulfonamide resistance and availability of more effective urinary tract infection treatments.

Masse moléculaire

294,3300 g/mol

LogP

0,10

TPSA

113,00 Å²

Règle des 5 de Lipinski

Conforme

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

CCn1ccc(NS(=O)(=O)c2ccc(N)cc2)nc1=O

InChI

InChI=1S/C12H14N4O3S/c1-2-16-8-7-11(14-12(16)17)15-20(18,19)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,15,17)

Molecular Formula

C12H14N4O3S

HBD / HBA

2 / 4

Liaisons Rotatives

4

Atomes Lourds

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

Sulfacytine is a short-acting sulfonamide antibiotic used for the treatment of acute, uncomplicated urinary tract infections caused by susceptible bacteria. It inhibits bacterial dihydropteroate synthase, blocking folate synthesis and selectively killing bacteria that must synthesize their own folic acid. Its use has declined with the emergence of sulfonamide resistance and availability of more effective urinary tract infection treatments.

Yes, Sulfacytine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201056. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5322. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Données Clés

Formule: C12H14N4O3S

Liens externes

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.