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Tramadol Hydrochloride

CHEMBL1237065 Phase 4 Approuvé Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
299.8 g/mol
LogP
—
Phase
4

A hydrochloride salt form of tramadol with the same therapeutic properties. This prescription pain reliever is used to treat moderate to moderately severe pain and works through a combination of opioid receptor binding and inhibition of serotonin and norepinephrine reuptake in the brain.

Masse moléculaire

299,8300 g/mol

TPSA

32,70 Ų

Aires thérapeutiques

Pain Management Migraine Breast Cancer Chronic Pain

Mécanisme d'action

Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1cccc(C2(O)CCCCC2CN(C)C)c1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H26ClNO2

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
Liaisons Rotatives

                        
4

                    

                    
                    
                    

                        
Atomes Lourds

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
A hydrochloride salt form of tramadol with the same therapeutic properties. This prescription pain reliever is used to treat moderate to moderately severe pain and works through a combination of opioid receptor binding and inhibition of serotonin and norepinephrine reuptake in the brain.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Tramadol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1237065.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 63013.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.