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Tramadol Hydrochloride

CHEMBL1237065 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
299.8 g/mol
LogP
—
Phase
4

A hydrochloride salt form of tramadol with the same therapeutic properties. This prescription pain reliever is used to treat moderate to moderately severe pain and works through a combination of opioid receptor binding and inhibition of serotonin and norepinephrine reuptake in the brain.

分子量

299.8300 g/mol

TPSA

32.70 Ų

治疗领域

Pain Management Migraine Breast Cancer Chronic Pain

作用机制

Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

二维结构

SVG PNG

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SMILES

                    
COc1cccc(C2(O)CCCCC2CN(C)C)c1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H26ClNO2

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
可旋转键数

                        
4

                    

                    
                    
                    

                        
重原子数

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
A hydrochloride salt form of tramadol with the same therapeutic properties. This prescription pain reliever is used to treat moderate to moderately severe pain and works through a combination of opioid receptor binding and inhibition of serotonin and norepinephrine reuptake in the brain.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Mu-opioid receptor agonist and serotonin-norepinephrine reuptake inhibitor.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Tramadol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1237065.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 63013.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.