Trisilicate
Magnesium trisilicate is an inorganic antacid compound that neutralizes gastric acid by reacting with hydrochloric acid to form magnesium chloride and silicon dioxide, providing symptomatic relief from acid-related disorders. It is used for gastroesophageal reflux disease, peptic ulcers, and dyspepsia, and also acts as an adsorbent that can bind bile acids in the stomach. Its prolonged buffering action and low sodium content make it suitable for long-term antacid therapy.
Masse moléculaire
216,2800 g/mol
TPSA
134,00 Ų
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
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SMILES
O=[Si](O)O[Si](O)(O)O[Si](=O)O
InChI
InChI=1S/H4O8Si3/c1-9(2)7-11(5,6)8-10(3)4/h1,3,5-6H
Molecular Formula
H4O8Si3
HBD / HBA
4 / 8
Liaisons Rotatives
4
Atomes Lourds
11
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
Magnesium trisilicate is an inorganic antacid compound that neutralizes gastric acid by reacting with hydrochloric acid to form magnesium chloride and silicon dioxide, providing symptomatic relief from acid-related disorders. It is used for gastroesophageal reflux disease, peptic ulcers, and dyspepsia, and also acts as an adsorbent that can bind bile acids in the stomach. Its prolonged buffering action and low sodium content make it suitable for long-term antacid therapy.
Yes, Trisilicate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2109882. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5311267. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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