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Trisilicate

CHEMBL2109882 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
216.3 g/mol
LogP
—
Phase
4

Magnesium trisilicate is an inorganic antacid compound that neutralizes gastric acid by reacting with hydrochloric acid to form magnesium chloride and silicon dioxide, providing symptomatic relief from acid-related disorders. It is used for gastroesophageal reflux disease, peptic ulcers, and dyspepsia, and also acts as an adsorbent that can bind bile acids in the stomach. Its prolonged buffering action and low sodium content make it suitable for long-term antacid therapy.

Khối lượng phân tử

216,2800 g/mol

TPSA

134,00 Ų

Lĩnh vực điều trị

Gastroesophageal Reflux Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=[Si](O)O[Si](O)(O)O[Si](=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/H4O8Si3/c1-9(2)7-11(5,6)8-10(3)4/h1,3,5-6H

                

                

                

                    
                    

                        
Molecular Formula

                        
H4O8Si3

                    

                    
                    

                        
HBD / HBA

                        
4 / 8

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Magnesium trisilicate is an inorganic antacid compound that neutralizes gastric acid by reacting with hydrochloric acid to form magnesium chloride and silicon dioxide, providing symptomatic relief from acid-related disorders. It is used for gastroesophageal reflux disease, peptic ulcers, and dyspepsia, and also acts as an adsorbent that can bind bile acids in the stomach. Its prolonged buffering action and low sodium content make it suitable for long-term antacid therapy.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Trisilicate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2109882.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5311267.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.