Half Maximal Effective Concentration (EC50)
EC50The concentration of a drug that produces 50% of its maximal response. A measure of drug potency — lower EC50 indicates higher potency. Used for graded dose-response relationships.
Exemples
- Comparing potency of two agonists
- Dose-response curve inflection point
- In vitro cell-based assays
Le saviez-vous ?
The concentration of a drug that produces 50% of its maximal response. A measure of drug potency — lower EC50 indicates higher potency. Used for graded dose-response relationships.