Half Maximal Inhibitory Concentration (IC50)
IC50The concentration of an inhibitor required to reduce a biological process by 50%. Used for enzyme inhibitors, receptor antagonists, and cytotoxicity assays. Context-dependent and not directly comparable across assays.
Exemples
- Statin IC50 for HMG-CoA reductase
- Kinase inhibitor IC50 panels
- Antimicrobial IC50
Le saviez-vous ?
The concentration of an inhibitor required to reduce a biological process by 50%. Used for enzyme inhibitors, receptor antagonists, and cytotoxicity assays. Context-dependent and not directly comparable across assays.