Potency

Pharmacodynamics

The amount of drug needed to produce a defined effect. Expressed as EC50 or ED50 — lower values indicate higher potency. Potency is clinically less important than efficacy and safety.

Exemples

  • Fentanyl more potent than morphine
  • Hydrochlorothiazide vs chlorthalidone
  • Potency affects dose, not max effect

Le saviez-vous ?

The amount of drug needed to produce a defined effect. Expressed as EC50 or ED50 — lower values indicate higher potency. Potency is clinically less important than efficacy and safety.