Trough Concentration (Cmin)

Cmin
Pharmacokinetics

The lowest plasma drug concentration reached just before the next scheduled dose (Cmin). Used for therapeutic drug monitoring of aminoglycosides, vancomycin, and immunosuppressants.

Exemples

  • Vancomycin trough 15-20 mg/L
  • Tacrolimus trough monitoring
  • Digoxin trough <2 ng/mL

Le saviez-vous ?

The lowest plasma drug concentration reached just before the next scheduled dose (Cmin). Used for therapeutic drug monitoring of aminoglycosides, vancomycin, and immunosuppressants.