Maximum Plasma Concentration (Cmax)
CmaxThe highest plasma drug concentration achieved after administration. Reflects the rate and extent of absorption for oral drugs. Key parameter for determining peak-related toxicity and efficacy.
Examples
- Higher Cmax with IV vs oral
- Food effects on Cmax
- Dose-proportional Cmax in linear PK
Did You Know?
The highest plasma drug concentration achieved after administration. Reflects the rate and extent of absorption for oral drugs. Key parameter for determining peak-related toxicity and efficacy.