Efficacy (Emax)

Emax
Pharmacodynamics

The maximum effect a drug can produce regardless of dose (Emax). Distinguished from potency (dose needed to produce a given effect). A full agonist has higher efficacy than a partial agonist at the same receptor.

Examples

  • Morphine (high efficacy)
  • Buprenorphine (lower efficacy ceiling)
  • Codeine (low efficacy)

Did You Know?

The maximum effect a drug can produce regardless of dose (Emax). Distinguished from potency (dose needed to produce a given effect). A full agonist has higher efficacy than a partial …