Captopril vs Celecoxib

## Captopril vs Celecoxib: Overview

This comparison examines the pharmacological differences between **Captopril** and **Celecoxib**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Celecoxib**: Selective COX-2 inhibitor.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Celecoxib — 11 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Celecoxib — C17H14F3N3O2S.

**Molecular Weight**: Captopril — 217.2850 g/mol; Celecoxib — 381.3730 g/mol.

**Type**: Captopril — Small molecule; Celecoxib — Small molecule.