Citalopram vs Sertraline

## Citalopram vs Sertraline: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Sertraline**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Sertraline**: Selective serotonin reuptake inhibitor (SSRI).

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Sertraline — 26 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Sertraline — C17H17Cl2N.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Sertraline — 306.2290 g/mol.

**Type**: Citalopram — Small molecule; Sertraline — Small molecule.