Same Indication

Digoxin vs Duloxetine

## Digoxin vs Duloxetine: Overview

This comparison examines the pharmacological differences between **Digoxin** and **Duloxetine**.

## Mechanism of Action

**Digoxin**: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

**Duloxetine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

## Pharmacokinetics

**Half-life**: Digoxin — 36-48 hours; Duloxetine — 12 hours.

## Chemical Properties

**Molecular Formula**: Digoxin — C41H64O14; Duloxetine — C18H19NOS.

**Molecular Weight**: Digoxin — 780.9430 g/mol; Duloxetine — 297.4150 g/mol.

**Type**: Digoxin — Small molecule; Duloxetine — Small molecule.