Donepezil vs Paroxetine

## Donepezil vs Paroxetine: Overview

This comparison examines the pharmacological differences between **Donepezil** and **Paroxetine**.

## Mechanism of Action

**Donepezil**: Reversible acetylcholinesterase inhibitor.

**Paroxetine**: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

## Pharmacokinetics

**Half-life**: Donepezil — 70 hours; Paroxetine — 21 hours.

## Chemical Properties

**Molecular Formula**: Donepezil — C24H29NO3; Paroxetine — C19H20FNO3.

**Molecular Weight**: Donepezil — 379.4920 g/mol; Paroxetine — 329.3730 g/mol.

**Type**: Donepezil — Small molecule; Paroxetine — Small molecule.