Fentanyl vs Hydrochlorothiazide

## Fentanyl vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Fentanyl** and **Hydrochlorothiazide**.

## Mechanism of Action

**Fentanyl**: Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Fentanyl — 2-4 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Fentanyl — C22H28N2O; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Fentanyl — 336.4700 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Fentanyl — Small molecule; Hydrochlorothiazide — Small molecule.