Furosemide vs Hydrochlorothiazide

## Furosemide vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Furosemide** and **Hydrochlorothiazide**.

## Mechanism of Action

**Furosemide**: Loop diuretic inhibiting Na-K-2Cl cotransporter.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Furosemide — 2 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Furosemide — C12H11ClN2O5S; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Furosemide — 330.7440 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Furosemide — Small molecule; Hydrochlorothiazide — Small molecule.