Hydrochlorothiazide vs Naproxen

## Hydrochlorothiazide vs Naproxen: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Naproxen**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Naproxen**: Non-selective COX inhibitor.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Naproxen — 12-17 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Naproxen — C14H14O3.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Naproxen — 230.2590 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Naproxen — Small molecule.