Baricitinib
A JAK1/JAK2 inhibitor that blocks the intracellular signaling pathways that drive inflammation in conditions such as rheumatoid arthritis and atopic dermatitis. It is taken by mouth once daily.
आणविक भार
371.4170 g/mol
LogP
-0.50
TPSA
129.00 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
दवा वर्ग
क्रिया का तंत्र
Selective JAK1 and JAK2 inhibitor blocking cytokine signaling involved in inflammation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selective JAK1 and JAK2 inhibitor blocking cytokine signaling involved in inflammation.
2D संरचना
Cite this structure
Embed this structure
SMILES
CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3ncnc4[nH]ccc34)cn2)C1
InChI
InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
Molecular Formula
C16H17N7O2S
HBD / HBA
1 / 7
घूर्णनीय बंधन
5
भारी परमाणु
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A JAK1/JAK2 inhibitor that blocks the intracellular signaling pathways that drive inflammation in conditions such as rheumatoid arthritis and atopic dermatitis. It is taken by mouth once daily.
Selective JAK1 and JAK2 inhibitor blocking cytokine signaling involved in inflammation.
Key pharmacokinetic parameters for Baricitinib: Half-life: 12 hours.
Yes, Baricitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2105759. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 44205240. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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