Cinoxacin

CHEMBL1208 Phase 4 अनुमोदित Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
262.2 g/mol
LogP
2.1
Phase
4

An older quinolone antibiotic used for the treatment and prevention of urinary tract infections caused by gram-negative bacteria, with a spectrum similar to nalidixic acid. It has been largely replaced by fluoroquinolone antibiotics with broader activity. It is no longer widely commercially available.

आणविक भार

262.2200 g/mol

LogP

2.10

TPSA

88.40 Ų

लिपिंस्की RO5

उत्तीर्ण

क्रिया का तंत्र

Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This leads to breakage of bacterial chromosomal DNA and rapid cell death.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This leads to breakage of bacterial chromosomal DNA and rapid cell death.

2D संरचना

SVG PNG

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SMILES

CCn1nc(C(=O)O)c(=O)c2cc3c(cc21)OCO3

InChI

InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)

Molecular Formula

C12H10N2O5

HBD / HBA

1 / 7

घूर्णनीय बंधन

2

भारी परमाणु

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

An older quinolone antibiotic used for the treatment and prevention of urinary tract infections caused by gram-negative bacteria, with a spectrum similar to nalidixic acid. It has been largely replaced by fluoroquinolone antibiotics with broader activity. It is no longer widely commercially available.

Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This leads to breakage of bacterial chromosomal DNA and rapid cell death.

Yes, Cinoxacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1208. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2762. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.