Dexmedetomidine Hydrochloride
The hydrochloride salt form of dexmedetomidine used intravenously for ICU sedation and monitored anesthesia care sedation. It produces cooperative sedation where patients remain arousable, making it valuable for neurological assessments.
आणविक भार
236.7400 g/mol
TPSA
28.70 Ų
चिकित्सीय क्षेत्र
क्रिया का तंत्र
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …
2D संरचना
Cite this structure
Embed this structure
SMILES
Cc1cccc([C@H](C)c2c[nH]cn2)c1C.Cl
InChI
InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
Molecular Formula
C13H17ClN2
HBD / HBA
2 / 1
घूर्णनीय बंधन
2
भारी परमाणु
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
The hydrochloride salt form of dexmedetomidine used intravenously for ICU sedation and monitored anesthesia care sedation. It produces cooperative sedation where patients remain arousable, making it valuable for neurological assessments.
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Yes, Dexmedetomidine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2106195. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6918081. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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