Dexmedetomidine Hydrochloride

CHEMBL2106195 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

236.7 g/mol

LogP

—

Phase

4

The hydrochloride salt form of dexmedetomidine used intravenously for ICU sedation and monitored anesthesia care sedation. It produces cooperative sedation where patients remain arousable, making it valuable for neurological assessments.

น้ำหนักโมเลกุล

236.7400 g/mol

TPSA

28.70 Å²

ด้านการรักษา

Pain Management Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Parkinson's Disease Schizophrenia Generalized Anxiety Disorder Insomnia Deep Vein Thrombosis / Pulmonary Embolism Obesity Hypertension Breast Cancer Chronic Pain Heart Failure Atrial Fibrillation

กลไกการออกฤทธิ์

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

โครงสร้าง 2 มิติ

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SMILES

Cc1cccc([C@H](C)c2c[nH]cn2)c1C.Cl

InChI

InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1

Molecular Formula

C13H17ClN2

HBD / HBA

2 / 1

พันธะที่หมุนได้

2

อะตอมหนัก

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

The hydrochloride salt form of dexmedetomidine used intravenously for ICU sedation and monitored anesthesia care sedation. It produces cooperative sedation where patients remain arousable, making it valuable for neurological assessments.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Dexmedetomidine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2106195. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6918081. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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โครงสร้าง

ข้อมูลด่วน

สูตร: C13H17ClN2
คำพ้องความหมาย: 9

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.