Lifitegrast

CHEMBL2048028 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

615.5 g/mol

LogP

4.7

Phase

4

An integrin antagonist eye drop used to treat the signs and symptoms of dry eye disease. It works by blocking the LFA-1/ICAM-1 interaction that drives inflammation on the surface of the eye.

आणविक भार

615.5000 g/mol

LogP

4.70

TPSA

142.00 Å²

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

ग्लूकोमा

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure

Embed this structure

SMILES

CS(=O)(=O)c1cccc(C[C@H](NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc4ccoc4c2)C3)C(=O)O)c1

InChI

InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1

Molecular Formula

C29H24Cl2N2O7S

HBD / HBA

2 / 7

घूर्णनीय बंधन

7

भारी परमाणु

41

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

An integrin antagonist eye drop used to treat the signs and symptoms of dry eye disease. It works by blocking the LFA-1/ICAM-1 interaction that drives inflammation on the surface of the eye.

Yes, Lifitegrast is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2048028. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 11965427. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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संरचना

त्वरित डेटा

सूत्र: C29H24Cl2N2O7S
पर्यायवाची: 1

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.