Lumefantrine

CHEMBL38827 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

528.9 g/mol

LogP

8.7

Phase

4

This antimalarial drug is used exclusively in combination with artemether to treat uncomplicated malaria caused by Plasmodium falciparum, including strains resistant to older drugs like chloroquine. It works by accumulating in infected red blood cells and interfering with the parasite's ability to detoxify heme, a byproduct of its digestion of hemoglobin.

आणविक भार

528.9000 g/mol

LogP

8.70

TPSA

23.50 Å²

लिपिंस्की RO5

अनुत्तीर्ण

चिकित्सीय क्षेत्र

HIV/एड्स क्षय रोग (ट्यूबरकुलोसिस) मलेरिया

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

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SMILES

CCCCN(CCCC)CC(O)c1cc(Cl)cc2c1-c1ccc(Cl)cc1/C2=C/c1ccc(Cl)cc1

InChI

InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-

Molecular Formula

C30H32Cl3NO

HBD / HBA

1 / 2

घूर्णनीय बंधन

10

भारी परमाणु

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

This antimalarial drug is used exclusively in combination with artemether to treat uncomplicated malaria caused by Plasmodium falciparum, including strains resistant to older drugs like chloroquine. It works by accumulating in infected red blood cells and interfering with the parasite's ability to detoxify heme, a byproduct of its digestion of hemoglobin.

Yes, Lumefantrine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL38827. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6437380. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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संरचना

त्वरित डेटा

सूत्र: C30H32Cl3NO
पर्यायवाची: 1

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.