Phenacetin
Phenacetin is an analgesic and antipyretic drug of the anilide class that was historically used for pain relief and fever reduction, acting through its active metabolite acetaminophen to inhibit prostaglandin synthesis. It has been withdrawn from clinical use in most countries due to its association with analgesic nephropathy, hemolytic anemia, and carcinogenicity with chronic use.
आणविक भार
179.2200 g/mol
LogP
1.60
TPSA
38.30 Ų
लिपिंस्की RO5
उत्तीर्ण
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D संरचना
Cite this structure
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SMILES
CCOc1ccc(NC(C)=O)cc1
InChI
InChI=1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
Molecular Formula
C10H13NO2
HBD / HBA
1 / 2
घूर्णनीय बंधन
3
भारी परमाणु
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
Phenacetin is an analgesic and antipyretic drug of the anilide class that was historically used for pain relief and fever reduction, acting through its active metabolite acetaminophen to inhibit prostaglandin synthesis. It has been withdrawn from clinical use in most countries due to its association with analgesic nephropathy, hemolytic anemia, and carcinogenicity with chronic use.
Yes, Phenacetin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL16073. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4754. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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