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Tecovirimat

CHEMBL1257073 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
376.3 g/mol
LogP
2.6
Phase
4

Tecovirimat is an antiviral agent that inhibits the VP37 protein of orthopoxviruses, blocking the wrapping of intracellular mature virions and thereby preventing efficient spread of the virus between cells and to extracellular environments. It is approved for the treatment of smallpox and has been used under emergency authorization for mpox (monkeypox), representing a key countermeasure in orthopoxvirus preparedness. Its highly selective mechanism targets a viral protein with no human homolog, providing a favorable safety profile.

आणविक भार

376.3000 g/mol

LogP

2.60

TPSA

66.50 Ų

लिपिंस्की RO5

उत्तीर्ण

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=C(NN1C(=O)[C@@H]2[C@@H]3C=C[C@@H]([C@H]4C[C@@H]34)[C@@H]2C1=O)c1ccc(C(F)(F)F)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C19H15F3N2O3/c20-19(21,22)9-3-1-8(2-4-9)16(25)23-24-17(26)14-10-5-6-11(13-7-12(10)13)15(14)18(24)27/h1-6,10-15H,7H2,(H,23,25)/t10-,11+,12+,13-,14-,15+

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H15F3N2O3

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
घूर्णनीय बंधन

                        
1

                    

                    
                    
                    

                        
भारी परमाणु

                        
27

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Tecovirimat is an antiviral agent that inhibits the VP37 protein of orthopoxviruses, blocking the wrapping of intracellular mature virions and thereby preventing efficient spread of the virus between cells and to extracellular environments. It is approved for the treatment of smallpox and has been used under emergency authorization for mpox (monkeypox), representing a key countermeasure in orthopoxvirus preparedness. Its highly selective mechanism targets a viral protein with no human homolog, providing a favorable safety profile.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Tecovirimat is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1257073.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 16124688.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.