Terodiline

CHEMBL363295 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

281.4 g/mol

LogP

5.0

Phase

4

Terodiline is an anticholinergic and calcium channel-blocking agent that was used for the treatment of urge urinary incontinence and overactive bladder through combined mechanisms of inhibiting detrusor muscle contraction. It was withdrawn from the market due to serious cardiac arrhythmias, including torsades de pointes, associated with QT prolongation. Its dual mechanism distinguished it from pure antimuscarinics but proved to have an unacceptable cardiac safety profile.

आणविक भार

281.4000 g/mol

LogP

5.00

TPSA

12.00 Å²

लिपिंस्की RO5

उत्तीर्ण

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

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SMILES

CC(CC(c1ccccc1)c1ccccc1)NC(C)(C)C

InChI

InChI=1S/C20H27N/c1-16(21-20(2,3)4)15-19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,16,19,21H,15H2,1-4H3

Molecular Formula

C20H27N

HBD / HBA

1 / 1

घूर्णनीय बंधन

6

भारी परमाणु

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

Terodiline is an anticholinergic and calcium channel-blocking agent that was used for the treatment of urge urinary incontinence and overactive bladder through combined mechanisms of inhibiting detrusor muscle contraction. It was withdrawn from the market due to serious cardiac arrhythmias, including torsades de pointes, associated with QT prolongation. Its dual mechanism distinguished it from pure antimuscarinics but proved to have an unacceptable cardiac safety profile.

Yes, Terodiline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL363295. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 23480. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

रोगी-अनुकूल जानकारी खोज रहे हैं?

Terodiline PillFYI पर

संरचना

त्वरित डेटा

सूत्र: C20H27N

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.