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Vinbarbital

CHEMBL503565 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
224.3 g/mol
LogP
1.7
Phase
4

Vinbarbital is a barbiturate derivative that enhances GABA-A receptor chloride channel conductance and inhibits glutamate-mediated excitatory neurotransmission, producing sedative, hypnotic, and anticonvulsant effects. Like other barbiturates, it was used for insomnia, anxiety, and seizure disorders. It has largely been replaced by benzodiazepines and newer agents due to its narrow therapeutic index and risk of dependence.

आणविक भार

224.2600 g/mol

LogP

1.70

TPSA

75.30 Ų

लिपिंस्की RO5

उत्तीर्ण

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC/C=C(\C)C1(CC)C(=O)NC(=O)NC1=O

                

                

                
                

                    
InChI

                    
InChI=1S/C11H16N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h6H,4-5H2,1-3H3,(H2,12,13,14,15,16)/b7-6+

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H16N2O3

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
घूर्णनीय बंधन

                        
3

                    

                    
                    
                    

                        
भारी परमाणु

                        
16

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
Vinbarbital is a barbiturate derivative that enhances GABA-A receptor chloride channel conductance and inhibits glutamate-mediated excitatory neurotransmission, producing sedative, hypnotic, and anticonvulsant effects. Like other barbiturates, it was used for insomnia, anxiety, and seizure disorders. It has largely been replaced by benzodiazepines and newer agents due to its narrow therapeutic index and risk of dependence.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Vinbarbital is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL503565.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5284636.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.