Vinbarbital

CHEMBL503565 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

224.3 g/mol

LogP

1.7

Phase

4

Vinbarbital is a barbiturate derivative that enhances GABA-A receptor chloride channel conductance and inhibits glutamate-mediated excitatory neurotransmission, producing sedative, hypnotic, and anticonvulsant effects. Like other barbiturates, it was used for insomnia, anxiety, and seizure disorders. It has largely been replaced by benzodiazepines and newer agents due to its narrow therapeutic index and risk of dependence.

분자량

224.2600 g/mol

LogP

1.70

TPSA

75.30 Å²

리핀스키 5의 법칙

통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

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SMILES

CC/C=C(\C)C1(CC)C(=O)NC(=O)NC1=O

InChI

InChI=1S/C11H16N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h6H,4-5H2,1-3H3,(H2,12,13,14,15,16)/b7-6+

Molecular Formula

C11H16N2O3

HBD / HBA

2 / 3

회전 가능 결합

3

무거운 원자

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Vinbarbital is a barbiturate derivative that enhances GABA-A receptor chloride channel conductance and inhibits glutamate-mediated excitatory neurotransmission, producing sedative, hypnotic, and anticonvulsant effects. Like other barbiturates, it was used for insomnia, anxiety, and seizure disorders. It has largely been replaced by benzodiazepines and newer agents due to its narrow therapeutic index and risk of dependence.

Yes, Vinbarbital is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL503565. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5284636. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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분자식: C11H16N2O3

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.