Vitamin K
Vitamin K is a fat-soluble cofactor essential for the hepatic carboxylation of glutamic acid residues in coagulation factors (II, VII, IX, X) and natural anticoagulant proteins (C, S, Z) by gamma-glutamyl carboxylase, enabling calcium binding and coagulation cascade activation. Pharmacologically, vitamin K1 (phylloquinone) is used to reverse warfarin-induced anticoagulation and treat coagulopathy due to vitamin K deficiency or liver disease. Vitamin K2 (menaquinone) has roles in bone metabolism and vascular calcification prevention.
आणविक भार
450.7000 g/mol
LogP
10.90
TPSA
34.10 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
क्रिया का तंत्र
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
SMILES
CC1=C(C(=O)C2=CC=CC=C2C1=O)C/C=C(\C)/CCCC(C)CCCC(C)CCCC(C)C
InChI
InChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+
Molecular Formula
C31H46O2
HBD / HBA
- / 2
घूर्णनीय बंधन
14
भारी परमाणु
33
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
Vitamin K is a fat-soluble cofactor essential for the hepatic carboxylation of glutamic acid residues in coagulation factors (II, VII, IX, X) and natural anticoagulant proteins (C, S, Z) by gamma-glutamyl carboxylase, enabling calcium binding and coagulation cascade activation. Pharmacologically, vitamin K1 (phylloquinone) is used to reverse warfarin-induced anticoagulation and treat coagulopathy due to vitamin K deficiency or liver disease. Vitamin K2 (menaquinone) has roles in bone metabolism and vascular calcification prevention.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Vitamin K is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201519. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5280483. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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