Vitamin K
Vitamin K is a fat-soluble cofactor essential for the hepatic carboxylation of glutamic acid residues in coagulation factors (II, VII, IX, X) and natural anticoagulant proteins (C, S, Z) by gamma-glutamyl carboxylase, enabling calcium binding and coagulation cascade activation. Pharmacologically, vitamin K1 (phylloquinone) is used to reverse warfarin-induced anticoagulation and treat coagulopathy due to vitamin K deficiency or liver disease. Vitamin K2 (menaquinone) has roles in bone metabolism and vascular calcification prevention.
Молекулярная масса
450,7000 g/mol
LogP
10,90
TPSA
34,10 Ų
Правило пяти Липинского
Соответствует
Терапевтические области
Механизм действия
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
SMILES
CC1=C(C(=O)C2=CC=CC=C2C1=O)C/C=C(\C)/CCCC(C)CCCC(C)CCCC(C)C
InChI
InChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+
Molecular Formula
C31H46O2
HBD / HBA
- / 2
Вращаемые Связи
14
Тяжёлые Атомы
33
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
Vitamin K is a fat-soluble cofactor essential for the hepatic carboxylation of glutamic acid residues in coagulation factors (II, VII, IX, X) and natural anticoagulant proteins (C, S, Z) by gamma-glutamyl carboxylase, enabling calcium binding and coagulation cascade activation. Pharmacologically, vitamin K1 (phylloquinone) is used to reverse warfarin-induced anticoagulation and treat coagulopathy due to vitamin K deficiency or liver disease. Vitamin K2 (menaquinone) has roles in bone metabolism and vascular calcification prevention.
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.
Yes, Vitamin K is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201519. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5280483. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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