Maintenance Dose

Pharmacokinetics

The dose given at regular intervals to maintain steady-state therapeutic concentrations. Equals the amount eliminated per dosing interval. Adjusted for renal/hepatic impairment.

उदाहरण

  • MD = CL * Css * tau / F
  • Renal dose adjustment for aminoglycosides
  • Hepatic dose adjustment for opioids

क्या आप जानते हैं?

The dose given at regular intervals to maintain steady-state therapeutic concentrations. Equals the amount eliminated per dosing interval. Adjusted for renal/hepatic impairment.