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Nephrotoxicity

Toxicology

Drug-induced kidney injury affecting glomerular filtration, tubular secretion/reabsorption, or renal blood flow. Can manifest as acute kidney injury, chronic kidney disease, electrolyte imbalances, or nephrotic syndrome. Monitored through serum creatinine, BUN, estimated GFR, and urine biomarkers (KIM-1, NGAL).

उदाहरण

  • Aminoglycoside tubular toxicity (gentamicin, tobramycin)
  • Cisplatin proximal tubule damage requiring hydration
  • NSAID-induced renal vasoconstriction and AKI

क्या आप जानते हैं?

Drug-induced kidney injury affecting glomerular filtration, tubular secretion/reabsorption, or renal blood flow. Can manifest as acute kidney injury, chronic kidney disease, electrolyte imbalances, or nephrotic syndrome. Monitored through serum creatinine, …