Azithromycin vs Norfloxacin

Azithromycin vs Norfloxacin: Overview

This comparison examines the pharmacological differences between Azithromycin and Norfloxacin.

Mechanism of Action

Azithromycin: Binds 50S ribosomal subunit, inhibiting bacterial protein synthesis.

Norfloxacin: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

Pharmacokinetics

Half-life: Azithromycin — 68 hours; Norfloxacin — 3-4 hours.

Chemical Properties

Molecular Formula: Azithromycin — C38H72N2O12; Norfloxacin — C16H18FN3O3.

Molecular Weight: Azithromycin — 748.9840 g/mol; Norfloxacin — 319.3310 g/mol.

Type: Azithromycin — Small molecule; Norfloxacin — Small molecule.