Cedazuridine

CHEMBL3237547 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

268.2 g/mol

LogP

-1.1

Phase

4

A cytidine deaminase inhibitor that is co-administered with the chemotherapy agent decitabine to block its degradation in the gut and increase oral bioavailability. This combination allows for oral administration of decitabine, which previously required intravenous infusion. It is used in adults with myelodysplastic syndromes and chronic myelomonocytic leukemia.

Berat Molekul

268,2100 g/mol

LogP

-1,10

TPSA

102,00 Å²

Lipinski RO5

Lulus

Area Terapeutik

Melanoma Lymphoma Breast Cancer Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

SVG PNG

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SMILES

O=C1N[C@H](O)CCN1[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F

InChI

InChI=1S/C9H14F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h4-7,14-16H,1-3H2,(H,12,17)/t4-,5-,6-,7-/m1/s1

Molecular Formula

C9H14F2N2O5

HBD / HBA

4 / 7

Ikatan yang Dapat Dirotasi

2

Atom Berat

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

A cytidine deaminase inhibitor that is co-administered with the chemotherapy agent decitabine to block its degradation in the gut and increase oral bioavailability. This combination allows for oral administration of decitabine, which previously required intravenous infusion. It is used in adults with myelodysplastic syndromes and chronic myelomonocytic leukemia.

Yes, Cedazuridine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3237547. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 25267009. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Cedazuridine di PillFYI

Struktur

Data Cepat

Rumus: C9H14F2N2O5
Sinonim: 1

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.