Moxalactam

CHEMBL74632 Phase 4 Disetujui Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
520.5 g/mol
LogP
-0.6
Phase
4

This third-generation cephalosporin antibiotic with unusual oxacephem structure had good activity against gram-negative bacteria and anaerobes but was associated with serious bleeding problems due to interference with vitamin K-dependent clotting factors. It has been largely replaced by safer cephalosporins and other antibiotics.

Berat Molekul

520,5000 g/mol

LogP

-0,60

TPSA

232,00 Ų

Lipinski RO5

Gagal

Mekanisme Kerja

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mekanisme

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Struktur 2D

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

CO[C@@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CO[C@@H]21

InChI

InChI=1S/C20H20N6O9S/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32)/t12?,18-,20+/m1/s1

Molecular Formula

C20H20N6O9S

HBD / HBA

4 / 13

Ikatan yang Dapat Dirotasi

9

Atom Berat

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

This third-generation cephalosporin antibiotic with unusual oxacephem structure had good activity against gram-negative bacteria and anaerobes but was associated with serious bleeding problems due to interference with vitamin K-dependent clotting factors. It has been largely replaced by safer cephalosporins and other antibiotics.

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Yes, Moxalactam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL74632. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 47499. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.