Rufinamide
An anticonvulsant used primarily as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome, a severe childhood epilepsy disorder. It works by modulating sodium channel activity in neurons to reduce the frequency and severity of seizures.
Berat Molekul
238,1900 g/mol
LogP
0,70
TPSA
73,80 Ų
Lipinski RO5
Lulus
Area Terapeutik
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Struktur 2D
Cite this structure
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SMILES
NC(=O)c1cn(Cc2c(F)cccc2F)nn1
InChI
InChI=1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3,5H,4H2,(H2,13,17)
Molecular Formula
C10H8F2N4O
HBD / HBA
1 / 5
Ikatan yang Dapat Dirotasi
3
Atom Berat
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Pertanyaan yang Sering Diajukan
An anticonvulsant used primarily as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome, a severe childhood epilepsy disorder. It works by modulating sodium channel activity in neurons to reduce the frequency and severity of seizures.
Yes, Rufinamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201754. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 129228. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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