Saxagliptin Hydrochloride

CHEMBL1201743 Phase 4 Disetujui Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

351.9 g/mol

LogP

—

Phase

4

Saxagliptin hydrochloride is the hydrochloride salt of saxagliptin, a selective DPP-4 inhibitor that prolongs the activity of incretin hormones GLP-1 and GIP to stimulate glucose-dependent insulin secretion and suppress glucagon in type 2 diabetes. By inhibiting DPP-4, it prevents rapid degradation of endogenous incretins, enhancing postprandial glucose control with a low risk of hypoglycemia. It is used as monotherapy or in combination with other antidiabetic agents.

Berat Molekul

351,9000 g/mol

TPSA

90,40 Å²

Area Terapeutik

Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Struktur 2D

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SMILES

Cl.N#C[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2

InChI

InChI=1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

Molecular Formula

C18H26ClN3O2

HBD / HBA

3 / 4

Ikatan yang Dapat Dirotasi

2

Atom Berat

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Pertanyaan yang Sering Diajukan

Saxagliptin hydrochloride is the hydrochloride salt of saxagliptin, a selective DPP-4 inhibitor that prolongs the activity of incretin hormones GLP-1 and GIP to stimulate glucose-dependent insulin secretion and suppress glucagon in type 2 diabetes. By inhibiting DPP-4, it prevents rapid degradation of endogenous incretins, enhancing postprandial glucose control with a low risk of hypoglycemia. It is used as monotherapy or in combination with other antidiabetic agents.

Yes, Saxagliptin Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201743. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 49800073. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Data Cepat

Rumus: C18H26ClN3O2
Sinonim: 1

Tautan Eksternal

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Penyangkalan Medis

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.